Lei WT, et al. Incidence and risk factors for recurrent Henoch-Schönlein purpura in children from a 16-year nationwide database. Pediatr Rheumatol Online J. 2018 Apr 16;16(1):25.
Ours was the first study to describe the incidence of recurrent HSP, and added evidence of increased associations of recurrent HSP and allergic rhinitis, renal involvement, and steroid treatment for > 10 days. These results can be considered observations from real-world conditions. Patients with the aforementioned clinical features were suggested to receive longer periods of follow-up than previously suggested for the early identification and management of recurrent HSP. In those with a second HSP episode, perhaps 6 more months of monitoring is also suggested for the early recognition of a third HSP recurrence. Further study is needed to clarify the underlying pathogenic mechanisms of these associations.
Alfredo CS, et al. Henoch-Schönlein purpura: recurrence and chronicity. J Pediatr (Rio J). 2007 Mar-Apr;83(2):177-80.
“Our data reiterates the need for periodic follow-up of all children with HSP, especially in cases with renal involvement, such as, for example, those with persistent hematuria and proteinuria or arterial hypertension. Urinary sediments should be monitored, even in asymptomatic patients. Referral to a specialist (pediatric rheumatologist or nephrologist) is recommended in cases where presentation is atypical.”